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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
22.38
Human Site:
T6
Identified Species:
30.77
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
T6
_
_
M
P
R
K
G
T
Q
P
S
T
A
R
R
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
T6
_
_
M
P
R
K
G
T
Q
P
S
T
A
R
R
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
T6
_
_
M
P
R
K
G
T
Q
P
S
T
A
R
R
Dog
Lupus familis
XP_535848
1288
147094
T6
_
_
M
P
R
K
G
T
Q
P
S
T
A
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
T6
_
_
M
R
R
K
G
T
K
P
S
T
A
C
H
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
L6
_
_
M
G
F
L
K
L
I
E
I
E
N
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
Chicken
Gallus gallus
NP_989849
1274
145838
E23
A
E
A
V
S
N
E
E
S
D
N
R
S
L
E
Frog
Xenopus laevis
P50532
1290
146971
T6
_
_
M
P
P
K
K
T
K
T
S
T
A
V
A
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
S6
_
_
M
P
V
K
T
S
K
T
A
G
R
R
A
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
K7
_
M
P
S
R
T
T
K
A
S
T
A
A
A
K
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
A21
P
F
P
S
P
V
T
A
D
P
E
P
G
A
T
Honey Bee
Apis mellifera
XP_396862
1282
148175
M6
_
_
M
S
I
P
D
M
D
M
E
I
D
E
E
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
E14
A
A
P
P
Q
S
D
E
S
D
S
D
F
D
D
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
E25
H
S
V
E
I
I
K
E
F
P
I
L
I
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
P6
_
_
M
E
E
D
E
P
M
G
G
G
E
S
E
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
P78
N
R
Y
A
F
S
Q
P
T
N
S
T
T
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
100
100
N.A.
69.2
7.6
N.A.
0
0
53.8
30.7
14.2
6.6
7.6
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
76.9
15.3
N.A.
0
13.3
61.5
53.8
28.5
6.6
7.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
7.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
7.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
6
6
6
0
0
0
6
6
0
6
6
42
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
0
0
0
0
0
6
12
0
12
12
0
6
6
6
6
% D
% Glu:
0
6
0
12
6
0
12
18
0
6
12
6
6
12
18
% E
% Phe:
0
6
0
0
12
0
0
0
6
0
0
0
6
6
0
% F
% Gly:
0
0
0
6
0
0
30
0
0
6
6
12
6
0
0
% G
% His:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% H
% Ile:
0
0
0
0
12
6
0
0
6
0
12
6
6
0
0
% I
% Lys:
0
0
0
0
0
42
18
6
18
0
0
0
0
0
18
% K
% Leu:
0
0
0
0
0
6
0
6
0
0
0
6
0
6
0
% L
% Met:
0
6
59
0
0
0
0
6
6
6
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
6
0
0
0
6
6
0
6
0
0
% N
% Pro:
6
0
18
42
12
6
0
12
0
42
0
6
0
0
0
% P
% Gln:
0
0
0
0
6
0
6
0
24
0
0
0
0
0
0
% Q
% Arg:
0
6
0
6
36
0
0
0
0
0
0
6
6
30
24
% R
% Ser:
0
6
0
18
6
12
0
6
12
6
48
0
6
6
6
% S
% Thr:
0
0
0
0
0
6
18
36
6
12
6
42
6
6
6
% T
% Val:
0
0
6
6
6
6
0
0
0
0
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
65
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% _